JA-Gavin Church Yard - The Aurum Institute

Resistance to Mycobacterium tuberculosis infection among household contacts: a multinational study.

Baliashvili, D., Gandhi, N.R., Kim, S., Hughes, M., Mave, V., Mendoza-Ticona, A., Gonzales, P., Kim, N., Selvamuthu, P., Badal-Faesen, S. and Upton, C., 2021. Resistance to Mycobacterium tuberculosis ...
Aurum at 11th IAS Conference on HIV science

Aurum experts recently presented at the 11th International Aids Society (IAS) Conference, which brought together thousands of HIV professionals virtually from 18 to 21 July. On the opening day of the...
Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial

Wallis, R.S., Ginindza, S., Beattie, T., Arjun, N., Sebe, M., Likoti, M., Edward, V.A., Rassool, M., Ahmed, K., Fielding, K. and Ahidjo, B.A., 2021. Adjunctive host-directed therapies for pulmonary tu...
The utility of repeat Xpert MTB/RIF testing to diagnose tuberculosis in HIV-positive adults with initial negative result.

Hanifa, Y., Fielding, K.L., Chihota, V.N., Adonis, L., Charalambous, S., Foster, N., Karstaedt, A., McCarthy, K., Nicol, M.P., Ndlovu, N.T. and Sinanovic, E., 2018. The utility of repeat Xpert MTB/RIF...
The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk.

Mulenga, H., Fiore-Gartland, A., Mendelsohn, S.C., Penn-Nicholson, A., Mbandi, S.K., Borate, B., Musvosvi, M., Tameris, M., Walzl, G., Naidoo, K. and Churchyard, G., 2022. The effect of host factors o...
Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners

Chihota, V.N., Ntshiqa, T., Maenetje, P., Mansukhani, R., Velen, K., Hawn, T.R., Wallis, R., Grant, A.D., Churchyard, G.J. and Fielding, K., 2022. Resistance to Mycobacterium tuberculosis infection am...
Clinical predictors of pulmonary tuberculosis among South African adults with HIV

Mendelsohn, S.C., Fiore-Gartland, A., Awany, D., Mulenga, H., Mbandi, S.K., Tameris, M., Walzl, G., Naidoo, K., Churchyard, G., Scriba, T.J. and Hatherill, M., 2022. Clinical predictors of pulmonary t...
High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis

Kim, S., Wu, X., Hughes, M.D., Upton, C., Narunsky, K., Mendoza-Ticona, A., Khajenoori, S., Gonzales, P., Badal-Faesen, S., Shenje, J. and Omoz-Oarhe, A., 2022. High Prevalence of Tuberculosis Infecti...
Plasma host protein biomarkers correlating with increasing mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with HIV

Singer, S.N., Ndumnego, O.C., Kim, R.S., Ndung'u, T., Anastos, K., French, A., Churchyard, G., Paramithiothis, E., Kasprowicz, V.O. and Achkar, J.M., 2022. Plasma host protein biomarkers correlating w...
Xpert MTB/RIF versus sputum microscopy as the initial diagnostic test for tuberculosis: a cluster-randomised trial embedded in South African roll-out of Xpert MTB/RIF

Churchyard, G.J., Stevens, W.S., Mametja, L.D., McCarthy, K.M., Chihota, V., Nicol, M.P., Erasmus, L.K., Ndjeka, N.O., Mvusi, L., Vassall, A. and Sinanovic, E., 2015. Xpert MTB/RIF versus sputum micro...
Annual Tuberculosis Preventive Therapy for Persons With HIV Infection

Churchyard, G., Cárdenas, V., Chihota, V., Mngadi, K., Sebe, M., Brumskine, W., Martinson, N., Yimer, G., Wang, S.H., Garcia-Basteiro, A.L. and Nguenha, D., 2021. Annual tuberculosis preventive thera...
Missed Opportunities for TB Investigation in Primary Care Clinics in South Africa: Experience from the XTEND Trial

Chihota, V.N., Ginindza, S., McCarthy, K., Grant, A.D., Churchyard, G. and Fielding, K., 2015. Missed opportunities for TB investigation in primary care clinics in South Africa: experience from the XT...
Scientific advances and the end of tuberculosis: a report from the Lancet Commission on Tuberculosis

Reid, M., Agbassi, Y.J.P., Arinaminpathy, N., Bercasio, A., Bhargava, A., Bhargava, M., Bloom, A., Cattamanchi, A., Chaisson, R., Chin, D. and Churchyard, G., 2023. Scientific advances and the end of ...
What is next for BCG revaccination to prevent tuberculosis?

White, R.G., Fiore-Gartland, A.J., Hanekom, W.A., Vekemans, J., Garcia-Basteiro, A.L., Churchyard, G., Rangaka, M.X., Frick, M., Behr, M.A., Hill, P.C. and Mave, V., 2024. What is next for BCG revacci...
Measuring indirect transmission-reducing effects in tuberculosis vaccine efficacy trials: Why and how?

Nelson, K.N., Churchyard, G., Cobelens, F., Hanekom, W.A., Hill, P.C., Lopman, B., Mave, V., Rangaka, M.X., Vekemans, J., White, R.G. and Wong, E.B., 2023. Measuring indirect transmission-reducing eff...
Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tuberculosis: a double-blind, randomised, placebo-controlled, p

Borges, Á.H. et al. (2025) ‘Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis disease recurrence in HIV‐negative adults successfully treated for dr...
Impact and cost-effectiveness of short-course tuberculosis preventive treatment for household contacts and people with HIV in 29 high-incidence countries: A modelling analysis

Ryckman, T., Weiser, J., Gombe, M., Turner, K., Soni, P., Tarlton, D., Mazhidova, N., Churchyard, G., Chaisson, R.E. and Dowdy, D.W., 2023. Impact and cost-effectiveness of short-course tuberculosis p...
Pragmatic cluster-randomized trial of home-based preventive treatment for TB in Ethiopia and South Africa (CHIP-TB).

Malhotra, A., Nonyane, B.A.S., Shirey, E., Mulder, C., Hippner, P., Mulatu, F., Ratshinanga, A., Mitiku, P., Cohn, S., Conradie, G. and Chihota, V., 2023. Pragmatic cluster-randomized trial of home-ba...
An aspiration to radically shorten phase 3 TB vaccine trials.

Hill, P.C., Cobelens, F., Martinez, L., Behr, M.A., Churchyard, G., Evans, T., Fiore-Gartland, A.J., Garcia-Basteiro, A.L., Hanekom, W., Rangaka, M.X. and Vekemans, J., 2023. An aspiration to radicall...
Qualification of the differential leukocyte count and immunophenotyping in cryopreserved ex vivo whole blood assay.

Imbratta, C., Gela, A., Bilek, N., Mabwe, S., Cloete, Y., Mortensen, R., Borges, Á.H., Maenetje, P., Mlotshwa, M., Churchyard, G. and Sudi, L., 2023. Qualification of the differential leukocyte count...

Resistance to Mycobacterium tuberculosis infection among household contacts: a multinational study.

Aurum at 11th IAS Conference on HIV science

Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial

The utility of repeat Xpert MTB/RIF testing to diagnose tuberculosis in HIV-positive adults with initial negative result.

The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk.

Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners

Clinical predictors of pulmonary tuberculosis among South African adults with HIV

High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis

Plasma host protein biomarkers correlating with increasing mycobacterium tuberculosis infection activity prior to tuberculosis diagnosis in people living with HIV

Xpert MTB/RIF versus sputum microscopy as the initial diagnostic test for tuberculosis: a cluster-randomised trial embedded in South African roll-out of Xpert MTB/RIF

Annual Tuberculosis Preventive Therapy for Persons With HIV Infection

Missed Opportunities for TB Investigation in Primary Care Clinics in South Africa: Experience from the XTEND Trial

Scientific advances and the end of tuberculosis: a report from the Lancet Commission on Tuberculosis

What is next for BCG revaccination to prevent tuberculosis?

Measuring indirect transmission-reducing effects in tuberculosis vaccine efficacy trials: Why and how?

Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tuberculosis: a double-blind, randomised, placebo-controlled, p

Impact and cost-effectiveness of short-course tuberculosis preventive treatment for household contacts and people with HIV in 29 high-incidence countries: A modelling analysis

Pragmatic cluster-randomized trial of home-based preventive treatment for TB in Ethiopia and South Africa (CHIP-TB).

An aspiration to radically shorten phase 3 TB vaccine trials.

Qualification of the differential leukocyte count and immunophenotyping in cryopreserved ex vivo whole blood assay.

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