Clinical Research
![Image](/images/2023/12/21/clinical-research.jpg)
Running clinical trials ranging from large scale public health studies, to highly regulated clinical trials of new medications.
Each clinical research site (CRS) brings a unique complement of skills, populations, facilities, and experience.
We have conducted more than 210 research studies and clinical trials at 5 main Clinical Research Centres in Klerksdorp, Rustenburg, Tembisa, Pretoria and Mozambique.
Conducted > 224 trials and research studies in the past 18 years focusing on:
HIV vaccines & prevention (oral, topical, and long-acting injectable PrEP)
TB treatment, Host-directed therapy, TB vaccines & TB preventative therapy
![This image for Image Layouts addon](/media/com_sppagebuilder/placeholder/icons-covid.png)
COVID-19 vaccines, COVID-19 mAb & COVID-19 treatment
Diagnostics and socio-behavioral studies.
Enrolled > 67 565 participants in trials and research studies (Clinical Research Division)
More than 23 500 Thibela TB (enrollment at mine shafts)
More than 25 500 Sisonke vaccine roll-out to Healthcare Workers (enrollment at Department of Health Vaccination Sites)
More than 18 513 enrolled in remaining trials and research studies (enrollment at 6 Clinical Research Sites)
Aurum’s distinct strengths:
CRS pluripotency
Collective scientific, operational & management experience of its research leadership
High-functioning resources & systems to effectively implement large-scale complex clinical trials (both network & Investigator-lead)
We focus on these programmatic areas:
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COVID-19
![Image](/images/pages/clinical-research-division/hiv-treatment-and-prep.png)
HIV Treatment & PreP
![Image](/images/2022/07/11/tb-treatment-1.png)
TB Treatment
![Image](/images/pages/clinical-research-division/icon-hiv-vaccine.png)
HIV Vaccine
![Image](/images/2022/07/11/tb-vaccine.png)
TB Vaccine
![Image](/images/pages/clinical-research-division/icons-special-projects1.png)
Special Projects
2023 AT A GLANCE
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276
Employees
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6
Clinical Research Sites
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1
Overnight / PK facility
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3
Routine Laboratories
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1
Basic Research Lab which includes a BSL-3 mycobacteriology lab
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1
Biorepository
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4
Registered Pharmacies
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33
Funders
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62
Clinical Trials Conducted in 2022
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5673
Participants
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26
Vaccine Trials
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28
Treatment & Prevention Trials
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11
Aurum Led Trials
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34
CRD Publications:
Aurum CRS Centres
![Pretoria CRS](/images/2023/12/20/pretoria-crs.jpg)
Pretoria CRS
Acquired to conduct Pharma & PK Trials.
78 trials > 3 400 enrolled.
78 trials > 3 400 enrolled.
![Fundação Aurum](/images/2023/12/20/aurum-moz.jpg)
Fundação Aurum
Established in Mozambique to aid roll out of 3HP & Covid-19 self-testing and prepare for TPT Phase 3 and 4 trials.
1 trials > 22 enrolled.
1 trials > 22 enrolled.
![Tembisa CRS](/images/2023/12/20/tembisa-crs.jpg)
Tembisa CRS
Established to conduct TB Treatment Trials Consists of 2 CRS’s (C1&2, C3&4)
C1&2: 42 Studies/Trials > 3 600 enrolled.
C3&4: 12 Studies/Trials > 2 400 enrolled.
C1&2: 42 Studies/Trials > 3 600 enrolled.
C3&4: 12 Studies/Trials > 2 400 enrolled.
![Rustenburg CRS](/images/2023/12/21/rustenburg-crs-.jpg)
Rustenburg CRS
Established to conduct HIV Epidemiology Studies to prepare for HIV Vaccine Trials.
47 trials > 1700 enrolled.
47 trials > 1700 enrolled.
![Klerksdorp CRS](/images/2023/12/20/klerksdorp-crs5.jpg)
Klerksdorp CRS
Established to conduct HIV Vaccine Trials.
46 trials > 17 800 enrolled.
46 trials > 17 800 enrolled.
![Image](/images/2024/01/22/tlhabane_vaccine_jab_9086.jpg)
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We have seen the impact of clinical trials saving millions of lives in the COVID-19 pandemic and we are now even more committed to continue our search for safer, more effective tools to address the continuing TB and HIV pandemics!
Our Team
Latest Highlights
Read the latest news about our work in clinical research