We have conducted more than 180 research studies and clinical trials at 4 main Clinical Research Centres in Klerksdorp, Rustenburg, Tembisa and Pretoria. These are each managed by a dedicated Programme Manager and an overarching HoD of Clinical Research Projects in addition to the site-based management team. Each site has a dedicated full time CRS Leader / PI and supporting Medical Officers, Nurses, Study Co-ordinators, Quality Assurance and Control Officers, Data Capturers, Research assistants (Recruitment and Retention), Drivers, Operations Managers and General Assistants. Each Centre has access to various key populations and has established Community Advisory Boards.