JA-Robert Wallis - The Aurum Institute

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB–a study protocol

Rachow, A., Ivanova, O., Wallis, R., Charalambous, S., Jani, I., Bhatt, N., Kampmann, B., Sutherland, J., Ntinginya, N.E., Evans, D. and Lönnroth, K., Niemann, S.,Ulrich, E., Schaible, Geldmacher, C....
A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.

Imperial, M.Z., Nahid, P., Phillips, P.P., Davies, G.R., Fielding, K., Hanna, D., Hermann, D., Wallis, R.S., Johnson, J.L., Lienhardt, C. and Savic, R.M., 2018. A patient-level pooled analysis of trea...
Declines in lung function after antiretroviral therapy initiation in adults with human immunodeficiency virus and tuberculosis: a potential manifestation of respiratory immune reconstitution inflammatory syndrome.

Auld, S.C., Maenetje, P., Ravimohan, S., Weissman, D., Ncube, I., Mlotshwa, M., Ratsela, N., Chase, W., Vangu, M.D.T., Wallis, R. and Churchyard, G., 2020. Declines in lung function after antiretrovir...
Lung injury on antiretroviral therapy in adults with human immunodeficiency Virus/Tuberculosis.

Ravimohan, S., Auld, S.C., Maenetje, P., Ratsela, N., Mlotshwa, M., Ncube, I., Smith, J.P., Vangu, M.D.T., Sebe, M., Kossenkov, A. and Weissman, D., Wallis, R.S., Churchyard, G., Kornfeld, H., Bisson,...
A common NLRC4 gene variant associates with inflammation and pulmonary function in human immunodeficiency virus and tuberculosis.

Ravimohan, S., Maenetje, P., Auld, S.C., Ncube, I., Mlotshwa, M., Chase, W., Tiemessen, C.T., Vangu, M.D.T., Wallis, R.S., Churchyard, G., Weissman, D., Kornfeld, H., Bisson, G.P., 2019. A common NLRC...
An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19

Chimoyi, L., Velen, K., Churchyard, G.J., Wallis, R., Lewis, J.J. and Charalambous, S., 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of ...
An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19

Chimoyi, L., Velen, K., Churchyard, G.J., Wallis, R., Lewis, J.J. and Charalambous, S., 2020. An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of ...
Mycobacterial Growth Inhibition Assay (MGIA) as a Host Directed Diagnostic Tool for the Evaluation of the Immune Response in Subjects Living With Type 2 Diabetes Mellitus.

Bobadilla-del-Valle, M., Leal-Vega, F., Torres-Gonzalez, P., Ordaz-Vazquez, A., Garcia-Garcia, M.D.L., Tovar-Vargas, M., Delgado-Sanchez, G., Guerra De Blas, P.D.C., Wallis, R.S., Ponce-De-León, A. a...
Mycobacterial Growth Inhibition Assay (MGIA) as a Host Directed Diagnostic Tool for the Evaluation of the Immune Response in Subjects Living With Type 2 Diabetes Mellitus.

Bobadilla-del-Valle, M., Leal-Vega, F., Torres-Gonzalez, P., Ordaz-Vazquez, A., Garcia-Garcia, M.D.L., Tovar-Vargas, M., Delgado-Sanchez, G., Guerra De Blas, P.D.C., Wallis, R.S., Ponce-De-León, A. a...
Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial

Wallis, R.S., Ginindza, S., Beattie, T., Arjun, N., Sebe, M., Likoti, M., Edward, V.A., Rassool, M., Ahmed, K., Fielding, K. and Ahidjo, B.A., 2021. Adjunctive host-directed therapies for pulmonary tu...
Pulmonary restriction predicts long-term pulmonary impairment in people with HIV and tuberculosis.

Auld, S.C., Kornfeld, H., Maenetje, P., Mlotshwa, M., Chase, W., Vangu, M.D.T., Torigian, D.A., Wallis, R.S., Churchyard, G. and Bisson, G.P., 2021. Pulmonary restriction predicts long-term pulmonary ...
Lung and blood early biomarkers for host-directed tuberculosis therapies: Secondary outcome measures from a randomized controlled trial

Wallis, R.S., Ginindza, S., Beattie, T., Arjun, N., Likoti, M., Sebe, M., Edward, V.A., Rassool, M., Ahmed, K., Fielding, K. and Ahidjo, B.A., 2022. Lung and blood early biomarkers for host-directed t...
Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners

Chihota, V.N., Ntshiqa, T., Maenetje, P., Mansukhani, R., Velen, K., Hawn, T.R., Wallis, R., Grant, A.D., Churchyard, G.J. and Fielding, K., 2022. Resistance to Mycobacterium tuberculosis infection am...
Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion.

Simmons, J.D., Dill-McFarland, K.A., Stein, C.M., Van, P.T., Chihota, V., Ntshiqa, T., Maenetje, P., Peterson, G.J., Benchek, P., Nsereko, M. and Velen, K., 2022. Monocyte Transcriptional Responses to...
A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis

Dierig, A., Hoelscher, M., Schultz, S., Hoffmann, L., Jarchow-MacDonald, A., Svensson, E.M., Te Brake, L., Aarnoutse, R., Boeree, M., McHugh, T.D. and Wildner, L.M., 2023. A phase IIb, open-label, ran...
Host-directed immunotherapy of viral and bacterial infections: past, present and future.

Wallis, R.S., O’Garra, A., Sher, A. and Wack, A., 2023. Host-directed immunotherapy of viral and bacterial infections: past, present and future. Nature Reviews Immunology, 23(2), pp.121-133....
TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance.

Abhimanyu, Longlax SC, Nishiguchi T, Ladki M, Sheikh D, Martinez AL, Mace EM, Grimm SL, Caldwell T, Portillo Varela A, Sekhar RV, Mandalakas AM, Mlotshwa M, Ginidza S, Cirillo JD, Wallis RS, Netea MG,...
Adjunctive N-Acetylcysteine and Lung Function in Pulmonary Tuberculosis.

Wallis RS, Sabi I, Lalashowi J, Bakuli A, Mapamba D, Olomi W, Siyame E, Ngaraguza B, Chimbe O, Charalambous S, Rachow A, Ivanova O, Zurba L, Myombe B, Kunambi R, Hoelscher M, Ntinginya N, Churchyard G...
Repurposing N-acetylcysteine for management of non-acetaminophen induced acute liver failure: an evidence scan from a global health perspective.

Jerome RN, Zahn LA, Abner JJ, Joly MM, Shirey-Rice JK, Wallis RS, Bernard GR, Pulley JM. Repurposing N-acetylcysteine for management of non-acetaminophen induced acute liver failure: an evidence scan ...
Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis.

Maenetje P, Baik Y, Schramm DB, Vangu MDW, Wallis RS, Mlotshwa M, Tiemessen CT, Li Y, Kornfeld H, Churchyard G, Auld SC, Bisson GP. Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung ...

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB–a study protocol

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis.

Declines in lung function after antiretroviral therapy initiation in adults with human immunodeficiency virus and tuberculosis: a potential manifestation of respiratory immune reconstitution inflammatory syndrome.

Lung injury on antiretroviral therapy in adults with human immunodeficiency Virus/Tuberculosis.

A common NLRC4 gene variant associates with inflammation and pulmonary function in human immunodeficiency virus and tuberculosis.

An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19

An ecological study to evaluate the association of Bacillus Calmette-Guerin (BCG) vaccination on cases of SARS-CoV2 infection and mortality from COVID-19

Mycobacterial Growth Inhibition Assay (MGIA) as a Host Directed Diagnostic Tool for the Evaluation of the Immune Response in Subjects Living With Type 2 Diabetes Mellitus.

Mycobacterial Growth Inhibition Assay (MGIA) as a Host Directed Diagnostic Tool for the Evaluation of the Immune Response in Subjects Living With Type 2 Diabetes Mellitus.

Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial

Pulmonary restriction predicts long-term pulmonary impairment in people with HIV and tuberculosis.

Lung and blood early biomarkers for host-directed tuberculosis therapies: Secondary outcome measures from a randomized controlled trial

Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners

Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion.

Host-directed immunotherapy of viral and bacterial infections: past, present and future.

TCA metabolism regulates DNA hypermethylation in LPS and Mycobacterium tuberculosis-induced immune tolerance.

Adjunctive N-Acetylcysteine and Lung Function in Pulmonary Tuberculosis.

Repurposing N-acetylcysteine for management of non-acetaminophen induced acute liver failure: an evidence scan from a global health perspective.

Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis.

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