Prof Gavin Churchyard - The Aurum Institute

Simultaneous initiation of dolutegravir-based antiretroviral therapy and once-weekly rifapentine and isoniazid for tuberculosis prevention in antiretroviral-naive people with HIV: an open-label, non-randomised, phase 1/2 trial

Weld, E.D., Beattie, T., Moodley, J., Mapendere, M., Salles, I., Solans, B.P., Nonyane, B.A., Wiesner, L., Nielson, T., Edward, V.A. and Chihota, V., 2025. Simultaneous initiation of dolutegravir-base...
Improving access to tuberculosis preventive treatment for children in Ethiopia: designing a home-based contact management intervention for the CHIP-TB trial through formative research

Salazar-Austin, N., Bergman, A.J., Mulder, C., Tudor, C., Mulatu, F., Conradie, G., Chaisson, R.E., Golub, J.E., Churchyard, G., Bedru, A. and Kerrigan, D., 2024. Improving access to tuberculosis prev...
Adjunctive N-Acetylcysteine and Lung Function in Pulmonary Tuberculosis.

Wallis, R.S., Sabi, I., Lalashowi, J., Bakuli, A., Mapamba, D., Olomi, W., Siyame, E., Ngaraguza, B., Chimbe, O., Charalambous, S. and Rachow, A., 2024. Adjunctive N-acetylcysteine and lung function i...
45 Evaluation of Drug-Resistant Tuberculosis Guidelines and Outcomes by Treatment Site in South Africa.

Rhea, C.H., Chihota, V., Oladimeji, M., Rebeiro, A.P.F., Amorim, G., von Knorring, N., Omar, S.V., Ismail, F., Churchyard, G. and van der Heijden, Y., 2024. 45 Evaluation of Drug-Resistant Tuberculosi...
Overcoming barriers to scaling up tuberculosis preventive treatment for household contacts

Churchyard, G. and Salazar-Austin, N., 2024. Overcoming barriers to scaling up tuberculosis preventive treatment for household contacts. The Lancet Respiratory Medicine, 12(8), pp.582-583....
Target regimen profiles for tuberculosis treatment.

Lienhardt, C., Dooley, K.E., Nahid, P., Wells, C., Ryckman, T.S., Kendall, E.A., Davies, G., Brigden, G., Churchyard, G., Cirillo, D.M. and Di Meco, E., 2024. Target regimen profiles for tuberculosis ...
Implications of subclinical tuberculosis for vaccine trial design and global effect.

Churchyard, G.J., Houben, R.M., Fielding, K., Fiore-Gartland, A.L., Esmail, H., Grant, A.D., Rangaka, M.X., Behr, M., Garcia-Basteiro, A.L., Wong, E.B. and Hatherill, M., 2024. Implications of subclin...
Optimizing the cascade of prevention to protect people from tuberculosis: A potential game changer for reducing global tuberculosis incidence.

Matteelli, A., Churchyard, G., Cirillo, D., den Boon, S., Falzon, D., Hamada, Y., Houben, R.M., Kanchar, A., Kritski, A., Kumar, B. and Miller, C., 2024. Optimizing the cascade of prevention to protec...
Safety and immunogenicity of the H56:IC31 tuberculosis vaccine candidate in adults successfully treated for drug-susceptible pulmonary TB: a phase 1 randomized trial.

Tait, D., Diacon, A., Borges, Á.H., van Brakel, E., Hokey, D., Rutkowski, K.T., Hunt, D.J., Russell, M., Andersen, P.L., Kromann, I. and Ruhwald, M., 2024. Safety and Immunogenicity of the H56: IC31 ...
Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis.

Maenetje, P., Baik, Y., Schramm, D.B., Vangu, M.D.T.W., Wallis, R.S., Mlotshwa, M., Tiemessen, C.T., Li, Y., Kornfeld, H., Churchyard, G. and Auld, S.C., 2024. Circulating Biomarkers, Fraction of Exha...
What is next for BCG revaccination to prevent tuberculosis?

White, R.G., Fiore-Gartland, A.J., Hanekom, W.A., Vekemans, J., Garcia-Basteiro, A.L., Churchyard, G., Rangaka, M.X., Frick, M., Behr, M.A., Hill, P.C. and Mave, V., 2024. What is next for BCG revacci...
Tuberculosis Preventive Treatment in High TB‑Burden Settings: A State‑of‑the‑Art Review

Chihota, V., Gombe, M., Gupta, A., Salazar-Austin, N., Ryckman, T., Hoffmann, C.J., LaCourse, S., Mathad, J.S., Mave, V., Dooley, K.E. and Chaisson, R.E., 2024. Tuberculosis Preventive Treatment in Hi...
Immunogenicity, safety, and efficacy of the vaccine H56: IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tuberculosis: a double-blind, randomised, placebo-controlled,

Borges, Á.H., Russell, M., Tait, D., Scriba, T.J., Nemes, E., Skallerup, P., van Brakel, E., Cabibbe, A.M., Cirillo, D.M., Leuvennink-Steyn, M. and Rutkowski, K.T., 2025. Immunogenicity, safety, and...
Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data

Pelzer, P.T., Stuck, L., Martinez, L., Richards, A.S., Acuña-Villaorduña, C., Aronson, N.E., Bonnet, M., Carvalho, A.C., Chan, P.C., Huang, L.M. and Fang, C.T., 2025. Effectiveness of the primary Ba...
N-acetylcysteine modulates markers of oxidation, inflammation and infection in tuberculosis.

Mapamba, D.A., Sabi, I., Lalashowi, J., Sauli, E., Buza, J., Olomi, W., Mtafya, B., Kibona, M., Bakuli, A., Rachow, A. and Velen, K., 2025. N-acetylcysteine modulates markers of oxidation, inflammati...
The potential impact of new TB vaccines on the burden of TB in people living with HIV in South Africa.

Sumner, T., Clark, R.A., Prys-Jones, T.O., Bakker, R., Churchyard, G. and White, R.G., 2022. The potential impact of new TB vaccines on the burden of TB in people living with HIV in South Africa. AID...
BMI as a predictor of progression from TB infection to active TB in PLHIV.

Nguenha, D., Ndebele, F., Saavedra, B., Mambuque, E., Acácio, S., Cárdenas, V., Chihota, V., Grant, A., Yimer, G., Fielding, K. and Cobelens, F., 2025. BMI as a predictor of progression from TB inf...
Tuberculosis Preventive Treatment in High TB-Burden Settings: A State-of-the-Art Review

Chihota, V., Gombe, M., Gupta, A., Salazar-Austin, N., Ryckman, T., Hoffmann, C.J., LaCourse, S., Mathad, J.S., Mave, V., Dooley, K.E. and Chaisson, R.E., 2024. Tuberculosis Preventive Treatment in H...

Simultaneous initiation of dolutegravir-based antiretroviral therapy and once-weekly rifapentine and isoniazid for tuberculosis prevention in antiretroviral-naive people with HIV: an open-label, non-randomised, phase 1/2 trial

Improving access to tuberculosis preventive treatment for children in Ethiopia: designing a home-based contact management intervention for the CHIP-TB trial through formative research

Adjunctive N-Acetylcysteine and Lung Function in Pulmonary Tuberculosis.

45 Evaluation of Drug-Resistant Tuberculosis Guidelines and Outcomes by Treatment Site in South Africa.

Overcoming barriers to scaling up tuberculosis preventive treatment for household contacts

Target regimen profiles for tuberculosis treatment.

Implications of subclinical tuberculosis for vaccine trial design and global effect.

Optimizing the cascade of prevention to protect people from tuberculosis: A potential game changer for reducing global tuberculosis incidence.

Safety and immunogenicity of the H56:IC31 tuberculosis vaccine candidate in adults successfully treated for drug-susceptible pulmonary TB: a phase 1 randomized trial.

Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis.

What is next for BCG revaccination to prevent tuberculosis?

Tuberculosis Preventive Treatment in High TB‑Burden Settings: A State‑of‑the‑Art Review

Immunogenicity, safety, and efficacy of the vaccine H56: IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tuberculosis: a double-blind, randomised, placebo-controlled,

Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data

N-acetylcysteine modulates markers of oxidation, inflammation and infection in tuberculosis.

The potential impact of new TB vaccines on the burden of TB in people living with HIV in South Africa.

BMI as a predictor of progression from TB infection to active TB in PLHIV.

Tuberculosis Preventive Treatment in High TB-Burden Settings: A State-of-the-Art Review

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